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Genital herpes is caused by infection with the herpes simplex virus (HSV, usually type 2).

The female genital areas are on or near the pubis, vulva, labia, clitoris, buttocks or rectum.For the virus that causes herpes simplex, see Herpes simplex virus.Antibodies that develop following an initial infection with a type of HSV prevents reinfection with the same virus type a person with a history of orofacial infection caused by HSV-1 cannot contract herpes whitlow or a genital infection caused by HSV-1.If adolescents do not have antibodies to HSV-1 by the time they become sexually active, they may be more susceptible to genitally acquiring HSV-1 through oral sex.Women are more susceptible to HSV-2 infection because herpes is more easily transmitted from men to women than from women to men.HSV-2 infection is more common among women than among men (20.